Answer
$(y+5)(x+9)$
Work Step by Step
Using factoring by grouping, the given expression, $
xy+5x+9y+45
,$ is equivalent to
\begin{array}{l}\require{cancel}
(xy+5x)+(9y+45)
\\\\=
x(y+5)+9(y+5)
\\\\=
(y+5)(x+9)
.\end{array}
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