Answer
$\frac{16}{25}$
Work Step by Step
According to the definition of negative exponents, $a^{-n}=\frac{1}{a^{n}}$ (where $a\ne0$).
Therefore, $(\frac{5}{4})^{-2}=\frac{1}{(\frac{5}{4})^{2}}=\frac{4^{2}}{5^{2}}=\frac{16}{25}$.
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