Answer
$4x^{2/3}-9$
Work Step by Step
Using $(a+b)(a-b)=a^2-b^2$ or the product of the sum and difference of like terms, then,
\begin{array}{l}
(2x^{1/3}+3)(2x^{1/3}-3)
\\\\=
(2x^{1/3})^2-(3)^2
\\\\=
2^2x^{\frac{1}{3}\cdot2}-9
\\\\=
4x^{2/3}-9
.\end{array}