Answer
$e^{x+3}$
Work Step by Step
$\quad$
$\displaystyle \frac{d}{dx}[e^{u}]=e^{u}\cdot\frac{du}{dx}$
$u(x)=x+3$
$\displaystyle \frac{du}{dx}=1$
$\displaystyle \frac{d}{dx}[e^{x+3}]=e^{x+3}\cdot 1=e^{x+3}$
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