Answer
$\frac{\sqrt 5}{2}$
Work Step by Step
Step 1. Letting $tan^{-1}\frac{1}{2}=t$, we have $tan(t)=\frac{1}{2}$
Step 2. Let $x=2, y=1$, and $r=\sqrt {x^2+y^2}=\sqrt 5$.
Step 3. Sides $x,y,r$ form a right triangle with angle $t$ facing $y$.
Step 4. We have $sec(t)=\frac{r}{x}=\frac{\sqrt 5}{2}$ or $sec(tan^{-1}\frac{1}{2})=\frac{\sqrt 5}{2}$