Answer
$x\lt-3, x\gt5$
Work Step by Step
Since we are simplifying an absolute value, first solve for the original inequality, and then flip the sign and make the opposite side negative in the second inequality.
$-4|1-x|\lt-16$
$|1-x|\gt4$
$1-x\gt4$
$-3\gt x$
$x\lt-3$
$1-x\lt-4$
$x\gt5$
$x\lt-3, x\gt5$
