Answer
See below
Work Step by Step
Given $F(x)=5e^{-x}+4x$
Since, $D^2$ is the annihilator of $G(x)=4x$
Also, we have: $(D+1)$ is the annihilator of $H(x)=e^{-x}$.This implies that the $(D+1)$ is the annihilator of $5H(x)=5e^{-x}$
So, $F(x)=5H(x)+G(x)$
Therefore, $(D+1)D^2$ is the annihilator of F(x).