Answer
$F(x)=G(x)+5H(x)$
Therefore, $(D-7)^4(D^2+16)$ is the annihilator of $F(x)$.
Work Step by Step
We are given that $(D-7)^4$ is the annihilator of $G(x)=x^3 e^{7x}$
Also, we have: $D^2+16$ is the annihilator of $H(x)=\cos 4x$.This implies that the $D^2+16$ is the annihilator of $5 H(x)=5 \cos 4x$
So, $F(x)=G(x)+5H(x)$
Therefore, $(D-7)^4(D^2+16)$ is the annihilator of $F(x)$.