Answer
$\sqrt 5$.
Work Step by Step
1. Let $tan^{-1}(\frac{1}{2})=t$, we have $tan(t)=\frac{1}{2}$ and $t$ in quadrant I.
2. Let $x=2, y=1$, we have $r=\sqrt {(2)^2+(1)^2}=\sqrt {5}$.
3. Thus $csc(tan^{-1}(\frac{1}{2}))=csc(t)=\frac{r}{y}=\sqrt 5$.