## Elementary and Intermediate Algebra: Concepts & Applications (6th Edition)

$150$
The product of two numbers with opposite signs is negative while the product of two numbers with the same sign is positive. Multiplying the numbers from left-to-right, then the given expression, $-2\cdot(-5)\cdot(-3)\cdot(-5)$, simplifies to \begin{array}{l} 10\cdot(-3)\cdot(-5) \\\\= -30\cdot(-5) \\\\= 150 .\end{array}