Answer
$${y^2} = 20x$$
Work Step by Step
$$\eqalign{
& {\text{Focus }}\left( {5,0} \right){\text{ and vertex }}\left( {0,0} \right) \cr
& {\text{The focus of a parabola of the form }}{y^2} = 4px{\text{ is }}\left( {p,0} \right) \cr
& {\text{Focus }}\left( {5,0} \right) \cr
& {\text{Then }}p = 5 \cr
& {\text{And the equation is:}} \cr
& {y^2} = 4px \cr
& {y^2} = 4\left( 5 \right)x \cr
& {y^2} = 20x \cr} $$