Answer
$S_{21}=-399$
Work Step by Step
We are given:
$\sum_{n=0}^{20}(1-2n)$
Since the values go down by $-2$ consistently, this is an arithmetic sequence.
We find the first and last values of the sequence:
$a_0=1-2*0=1$
$a_{20}=1-2*20=-39$
Thus the partial sum is:
$S_{21}=\frac{21}{2}(1+-39)=-399$