Answer
$\dfrac{y^{12}z^{6}}{8}$
Work Step by Step
Using the laws of exponents, the given expression, $
(2y^{-4}z^{-2})^{-3}
$, is equivalent to
\begin{array}{l}\require{cancel}
2^{-3}y^{-4(-3)}z^{-2(-3)}
\\\\=
2^{-3}y^{12}z^{6}
\\\\=
\dfrac{y^{12}z^{6}}{2^{3}}
\\\\=
\dfrac{y^{12}z^{6}}{8}
.\end{array}