Essential Cell Biology, 4th Edition

Published by Garland Science
ISBN 10: 0815344546
ISBN 13: 978-0-81534-454-4

Chapter 18 - The Cell-Division Cycle - Questions - Page 644: Question 18-30 B

Answer

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Work Step by Step

In mutant cells that always express high levels of p21, the protein would continuously inhibit the activity of CDKs, leading to prolonged arrest of the cell cycle and a decreased rate of proliferation. This could potentially prevent the development of cancer .p21 is a protein that functions as a potent inhibitor of CDKs, including CDK2, which play a critical role in the regulation of the cell cycle.
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