## Calculus 8th Edition

$\lim\limits_{x \to 12^-}$f(t) = 150 $\lim\limits_{x \to 12^+}$f(t) = 300 The significance of the one-sided limits is that they show that the amount of drug in the patient's bloodstream begins decreasing the instant it enters the bloodstream. That is why there are holes in the graph.