Because installments were published so soon after Maupin wrote them, he was able to incorporate many current events into the plot of the series, as well as gauge reader response and modify the story accordingly.[4]
For example, Maupin once received a letter from a reader of the original serial, who pointed out that Anna Madrigal's name was an anagram for "A Man and a Girl", and Maupin "appropriated the idea".[4]
The AIDS epidemic of the 1980s affected San Francisco's gay community in particular (with many of Maupin's friends dying), which is reflected in the later books of the series.[5]
Real life people such as Jim Jones and a thinly veiled Elizabeth Taylor are mentioned in the story lines. A prominent closeted gay celebrity is represented as "______ ______" throughout the third novel, a reference to Rock Hudson, who was a friend of Maupin.[6]