In 1986, MCA Home Video released Frankenstein on LaserDisc. This release restored all the cut footage, as well as most of Frankenstein's "In the name of God!" line.[46][47] In the 1990s, MCA/Universal Home Video released the film on VHS as part of the "Universal Monsters Classic Collection", a series of releases of Universal Classic Monsters films.[48]
In 1999, Universal released Frankenstein on VHS and DVD as part of the "Classic Monster Collection"; this release restored the rest of the censored material.[49][50][51] In April 2004, Universal released Frankenstein: The Legacy Collection on DVD as part of the "Universal Legacy Collection".[52][53] This two-disc release includes Frankenstein, Bride of Frankenstein, Son of Frankenstein, The Ghost of Frankenstein and The House of Frankenstein.[52][53] In September 2006, Universal released Frankenstein on DVD as a two-disc "75th Anniversary Edition", as part of the "Universal Legacy Series".[54][55]
In 2012, Frankenstein was released on Blu-ray as part of the Universal Classic Monsters: The Essential Collection box set, which also includes a total of nine films from the Universal Classic Monsters series.[56][57] In September 2013, Frankenstein received a standalone Blu-ray release.[58] That same year, Frankenstein was included as part of the six-film Blu-ray set Universal Classic Monsters Collection, which also includes Dracula, The Mummy, The Invisible Man, Bride of Frankenstein, and The Wolf Man.[59] The next year, Universal released Frankenstein: Complete Legacy Collection on DVD.[60] This set contains eight films: Frankenstein, Bride of Frankenstein, Son of Frankenstein, Ghost of Frankenstein, Frankenstein Meets the Wolf Man, The House of Frankenstein, House of Dracula, and Abbott and Costello Meet Frankenstein.[60] In 2015, the six-film Universal Classic Monsters Collection was released on DVD.[61] In 2016, Frankenstein received a Walmart-exclusive Blu-ray release featuring a glow-in-the-dark cover.[62] That same year, the Complete Legacy Collection was released on Blu-ray.[63][64] In September 2017, the film received a Best Buy-exclusive steelbook Blu-ray release with cover artwork by Alex Ross.[65]
Frankenstein and its sequels were included in the Universal Classic Monsters: Complete 30-Film Collection Blu-ray box set in August 2018.[66][67] This box set also received a DVD release.[68] Later in October, Frankenstein was included as part of a limited edition Best Buy-exclusive Blu-ray set titled Universal Classic Monsters: The Essential Collection, which features artwork by Alex Ross.[69] Universal Pictures Home Entertainment released the film on 4K Ultra HD Blu-ray on October 5, 2021.[70]