Frankenstein was followed by a string of sequels, beginning with Bride of Frankenstein (1935), in which Elsa Lanchester plays the Monster's bride.
The next sequel, Son of Frankenstein (1939), was made, like all those that followed, without Whale or Clive (the latter of whom had died in 1937). This film featured Karloff's last full film performance as the Monster. Son of Frankenstein presented Basil Rathbone as Baron Wolf von Frankenstein, Bela Lugosi as bearded hunchback Ygor, and Lionel Atwill as Inspector Krogh.
The Ghost of Frankenstein was released in 1942. The film features Lon Chaney Jr. as the Monster, taking over from Boris Karloff, who played the role in the first three films of the series, and Bela Lugosi in his second appearance as the demented Ygor.
The fifth installment, Frankenstein Meets the Wolf Man was released in 1943, directed by Roy William Neill and starring Bela Lugosi as Frankenstein's monster. This is also the sequel to The Wolf Man, with Lon Chaney Jr. returning as the Wolf Man.
In the follow-up, House of Frankenstein (1944), Karloff returned to the series, but not to reprise his role as the monster, but as the Mad Doctor; the monster was this time portrayed by Glenn Strange. Chaney Jr. returned as the Wolf Man. Dracula was also featured in the film, played by John Carradine.
Its sequel, House of Dracula (1945), featured the same three monsters, Dracula, Frankenstein's monster and the Wolf Man with the same cast in their portrayals.
Many of the subsequent films which featured Frankenstein's monster demote the creature to a robotic henchman in someone else's plots, such as in its final Universal film appearance in the deliberately farcical Abbott and Costello Meet Frankenstein (1948) as well as the aforementioned House of Frankenstein and House of Dracula.