- Carmen Maura as Gloria: housewife and cleaning woman
- Ángel de Andrés López as Antonio: Gloria's husband, taxi driver and forger of letters
- Juan Martínez as Toni: their 14-year-old son and drug dealer
- Miguel Ángel Herranz as Miguel: their 12-year-old son
- Chus Lampreave as Grandmother: Antonio's mother who lives with them
- Verónica Forqué as Cristal: prostitute who lives in the same apartment block
- Kiti Manver as Juani: dressmaker who lives in the same apartment block
- Sonia Hohmann as Vanessa: Juani's daughter with telekinetic powers
- Gonzalo Suárez as Lucas Villalba: writer who meets Antonio in a taxi
- Amparo Soler Leal as Patricia: Villalba's wife
- Katia Loritz as Ingrid Müller: German woman, Antonio's former girlfriend
- Luis Hostalot as Polo: Policeman with erectile dysfunction
- Javier Gurruchaga as Dentist who wants to adopt Miguel
- Cecilia Roth as Woman in TV commercial
- Pedro Almodóvar as Playback 'La bien pagá'
- Tinín Almodóvar as Bank teller
- Carlitos as Dinero ("Money"): lizard
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