- In 1967 it was made into a French movie called L'invention de Morel.
- In 1974 it was made into an Italian movie called L'invenzione di Morel.
- In 1995 it was made into a puppet show featuring a real life actor as the fugitive.[4]
- The TV show Lost was partially based on "The Invention of Morel"; in Season 4, Episode 4, the character James 'Sawyer' Ford is seen reading the book.[5]
- In 2017 it had its world premiere as an opera (by Stewart Copeland) in a co-commission by Long Beach Opera and Chicago Opera Theater [6]
The 1961 movie Last Year at Marienbad has been attributed by many film critics[7][8] to be directly inspired by The Invention of Morel; however, screenwriter Alain Robbe-Grillet denied any influence of the book on the film (although Robbe-Grillet had read it and was familiar with Bioy Casares' work).[9]