Organic Chemistry (8th Edition)

Published by Pearson
ISBN 10: 0321768418
ISBN 13: 978-0-32176-841-4

Chapter 3 - Structure and Stereochemistry of Alkanes - Problems - Page 122: Problem 3-27 c

Answer

When two groups are cis and at carbons 1 and 4, both groups are up or down but one will be axial and the other will be equatorial.

Work Step by Step

Isopropyl is bulkier than ethyl, so the conformation with equatorial isopropyl is more stable.
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