Human Biology, 14 Edition

Published by McGraw-Hill Education
ISBN 10: 1-25924-574-8
ISBN 13: 978-1-25924-574-9

Chapter 21 - Engage - Page 475: 3

Answer

If we assume an equal number of male and female offspring, then the X-linked disorder would appear more frequently in males.

Work Step by Step

Males inherit only one X chromosome, so every time the male inherits an x-lined mutant gene, it should be expressed -whether it is recessive or dominant. In the case of females, two X chromosome are inherited: in this case if the mutant gene is recessive it would not be ex,pressed in a heterozygote genotype. Of course, only one of the two female X chromosomes is active--the other one becomes a Barr body--that makes the explanation more complicated. In any case, if the mutant gene is an autosomal gene, because there are corresponding loci for a trait (on homologous chromosomes) in males and females, an autosomal recessive trait would tend to be expressed with equal frequency in males and in females
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