Anatomy & Physiology: The Unity of Form and Function, 7th Edition

Published by McGraw-Hill Education
ISBN 10: 0073403717
ISBN 13: 978-0-07340-371-7

Chapter 7 - Section 7.2 - Histology of Osseous Tissue - Before You Go On - Page 209: 10


Step One: Development of Ossification Center-Osteoblasts secrete organic extracellular matrix Step Two: Calcification-Calcium and other mineral salts are deposited and extracellular matrix calcifies (hardens). Step Three: Formation of Trabeculae-Extracellular matrix develops into trabeculae that fuse to form spongy bone Step Four: Development of the Periosteum-Mesenchyme at the periphery of the bone develops into the periosteum. The flat bones of the skull and parts of the mandible and clavicle are formed by Intramembranous Ossification

Work Step by Step

Intramembranous Ossification Pg 208-209
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