Answer
The major digestive tract regulator enteroendocrine chemicals are Gastrin, ghrelin, histamine, somatostatin, gastric inhibitory peptide, cholecystokinin (CCK), vasoactive intestinal peptide(VIP) gastric inhibitory peptide (GIP)
Work Step by Step
Some of these substances are hormones that act through the blood system ; others are paracrines that act on adjacent cells or tissues. The gut-brain peptides are a special sub-group of thees substances that are produced both by GI tissues/cells and by cells/tissues in the central nervous system (CNS). Examples of gut-brain peptides are GIP, CCK, substance P, ghrelin, and neuropeptide Y (NPY)