Answer
$ŷ=-91.3+1.521x_1+0.441x_2$
Work Step by Step
In MINITAB, enter the Midterm values in C1, the Project values in C2 and the Course Grade values in C3.
Select Stats -> Regression -> Regression -> Fit Regression Model
Enter C3 in "Responses" and C1 C2 in "Continuous Predictors"
The least-squares regression line will be shown in "Regression Equation", where C3 is $ŷ$ (Course Grade), C1 is $x_1$ (Midterm) and C2 is $x_2$ (Project).
$ŷ=-91.3+1.521x_1+0.441x_2$
