Answer
$f(16)=47.3$
This tells us that 47.3 percent of college students are predicted to be taking at least one online course in 2016 (which is x=16 years after 2000).
Work Step by Step
We can find $f(16)$ by plugging $x=16$ into the given equation for $f(x)$.
$f(x)=2.7x+4.1$
$f(16)=2.7\times16+4.1=43.2+4.1=47.3$
