Answer
$4x^2-9y^2$
Work Step by Step
Using $(a-b)(a+b)=a^2-b^2$, or the product of the sum and difference of like terms, the given expression, $
(2x+3y)(2x-3y)
,$ is equivalent to
\begin{array}{l}\require{cancel}
(2x)^2-(3y)^2
\\\\=
4x^2-9y^2
.\end{array}