#### Answer

14,220

#### Work Step by Step

If we multiply 28.36 by 501.375, we get an answer of 14,218.995. In multiplication problems, we need to round the answer to the number of significant digits as the value with the least amount of significant figures, which is 28.36. This value has only four significant digits, so we need to round the answer to four significant digits. We then round the answer to 14,220, which has four significant figures.