Answer
$(-\infty, -4) \cup (-4, +\infty)$.
Work Step by Step
The denominator cannot be equal to zero since division of zero gives an undefined expression.
Thus, in the given expression, $x$ cannot be $-4$ since it will make the denominator zero.
Therefore, the domain of the given expression is any real number except $-4$.
In interval notation, the domain is:
$(-\infty, -4) \cup (-4, +\infty)$.