- Speak (talk show), American sports talk show
- SPEAK (test), the Speaking Proficiency English Assessment Kit from the Educational Testing Service
- Speak (The Tick), the pet of comic superhero The Tick
- Speak (Unix), a Unix utility
- Speak (imprint), young adult division of the publishing company the Penguin Group
- Wii Speak, a microphone accessory for Nintendo's Wii video game console
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