Ramona has been adapted several times for other media. The first was a silent film by the same name, released in 1910. It was directed by D. W. Griffith and starred Mary Pickford. Other versions were made in 1928, 1936 and 1946.
- Ramona (1910 film), a 17-minute short directed by D. W. Griffith
- Ramona (1916 film), directed by Donald Crisp
- Ramona (1928 film), directed by Edwin Carewe, featuring Dolores del Río and Warner Baxter
- Ramona (1936 film), directed by Henry King, featuring Loretta Young and Don Ameche
- Ramona (1946 film), directed by Víctor Urruchúa
- Screen Guild Theater, 1945 radio broadcast
- Ramona (2000 TV series), a Mexican telenovela
- The Ramona Pageant, an annual outdoor play, has been performed annually since 1923 in Hemet, California. The Ramona Pageant is the largest and longest-running outdoor play in the United States. It is the official state play of the State of California.