- Catch-22 was adapted into a feature film of the same name in 1970, directed by Mike Nichols.
- Catch-22 play: Aquila Theatre produced a stage adaptation of Catch-22, based on Heller's 1971 stage adaption. It was directed by Peter Meineck. This production toured the USA in 2007/8 with a Bexhill on Sea production in the fall of 2008.
- A pilot for a comedy series based upon Catch-22 was made and televised in 1973, with Richard Dreyfuss in the starring role of Capt. Yossarian.
- A six-episode miniseries produced by George Clooney has been picked up by Hulu for a straight-to-series order. Kyle Chandler will portray Colonel Cathcart.
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