Comics
Dark Horse Comics publishes a series of comic books based on the novel.
Television
Starz developed a television series from the novel with Bryan Fuller and Michael Green.[26] The series debuted in April 2017. At the end of season 1, Fuller stepped down as showrunner and was replaced by Jesse Alexander. The two had previously worked together on Star Trek: Discovery and Hannibal.[27]
Music
The power metal band Blind Guardian wrote a song titled "Secrets of the American Gods" based on the novel, on their 2022 album The God Machine.[28]