- Miles Teller as Andrew Neiman, an ambitious young jazz drummer at Shaffer Conservatory
- J. K. Simmons as Terence Fletcher, a ruthless jazz instructor at Shaffer
- Paul Reiser as Jim Neiman, Andrew's father, a writer turned high school teacher
- Melissa Benoist as Nicole, a movie theater employee who briefly dates Andrew
- Austin Stowell as Ryan Connolly, another drummer in Fletcher's band
- Nate Lang as Carl Tanner, another drummer in Fletcher's band
- Chris Mulkey as Uncle Frank Neiman, Andrew's uncle
- Damon Gupton as Mr. Kramer, Andrew's first instructor before being recruited by Fletcher
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