- Mac (Fainy McCreary) – A wandering printer, train-hopping newspaperman, and crusader for the working man
- Janey Williams – A young stenographer from Washington, D.C. (assistant to Moorehouse)
- Eleanor Stoddard – A cold, haughty young social climber
- J. Ward Moorehouse – A slick, influential public relations man
- Charley Anderson – A gullible, good-natured mechanic and flying ace
- Joe Williams – A rugged, slow-witted sailor, brother of Janey Williams
- Richard Ellsworth Savage – A Harvard graduate, employee of Moorehouse
- Daughter (Anne Elizabeth Trent) – A spirited Texas belle and volunteer nurse
- Eveline Hutchins – Artist and designer, Eleanor's long-time friend and rival
- Ben Compton – A law student and labor activist/revolutionary
- Mary French – Dedicated labor activist and journalist
- Margo Dowling – Attractive, cagey and adventurous, eventually a Hollywood actress
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