- Leonardo DiCaprio as Jordan Belfort
- Jonah Hill as Donnie Azoff
- Margot Robbie as Naomi Lapaglia
- Matthew McConaughey as Mark Hanna
- Kyle Chandler as FBI Agent Patrick Denham
- Rob Reiner as Max Belfort
- Jon Bernthal as Brad Bonick
- Jon Favreau as Manny Riskin
- Jean Dujardin as Jean Jacques Saurel
- Joanna Lumley as Aunt Emma
- Cristin Milioti as Teresa Petrillo
- Christine Ebersole as Leah Belfort
- Shea Whigham as Captain Ted Beecham
- Katarina Čas as Chantalle
- P. J. Byrne as Nicky Koskoff ("Rugrat")
- Kenneth Choi as Chester Ming
- Brian Sacca as Robbie Feinberg ("Pinhead")
- Henry Zebrowski as Alden Kupferberg ("Sea Otter")
- Ethan Suplee as Toby Welch
In addition, cameos and smaller roles include Bo Dietl as himself, the real Jordan Belfort as the Auckland Straight Line host at the end of the film, Thomas Middleditch as a Stratton broker whose goldfish is eaten by Donnie for slacking off, Jake Hoffman as Steve Madden, Fran Lebowitz as The Honorary [sic] Samantha Stogel, Edward Herrmann as the voice over the Stratton Oakmont commercial at the beginning of the film, and an uncredited Spike Jonze as Dwayne, the head of the Long Island brokerage firm who introduces Belfort to the world of penny stocks.[6]
