Film and television
The story was adapted as a short film released in 1921 as part of the Stoll film series, featuring Eille Norwood as Holmes.
The story is also alluded to in the BBC television series Sherlock where a yellow smiley face is painted on the wall of Sherlock's flat. Additionally, quotes from the story are used as plot points in "The Lying Detective". In addition, the town of Norbury from the story is represented in the episode "The Six Thatchers" in the form of Vivian Norbury, the main adversary of the episode.
Edith Meiser adapted the story as an episode of the American radio series The Adventures of Sherlock Holmes that was broadcast on 14 January 1932, with Richard Gordon as Holmes and Leigh Lovell as Watson.
"The Yellow Face" was dramatised by Gerry Jones for BBC Radio 4 in 1992 as an episode of the 1989–1998 radio series starring Clive Merrison as Holmes and Michael Williams as Watson. It featured Helena Breck as Effie Munro.
The story was adapted for radio in 2005 as part of The Classic Adventures of Sherlock Holmes, a series on the American radio show Imagination Theatre, with John Patrick Lowrie as Holmes and Lawrence Albert as Watson. It was the first episode in the series.