Molecular Biology of the Cell 6th Edition

Published by Garland Science
ISBN 10: 0815344325
ISBN 13: 978-0-81534-432-2

Chapter 5 - End-of-Chapter - Problems: 5-13

Answer

See the explanation below.

Work Step by Step

We must assume that the mutations caused by NHEJ are random throughout the genome, and only 2% of the genome is very crucial for cell survival and function. There is a 2% chance that the mutations may have occurred in the coding sequence. This then corresponds to about 40 genes in each of the cells. This deems it an ineffective mutation because it affects so little.
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