Chapter 8 - Energy, Enzymes, and Metabolism - 8.5 Enzyme Activities Can Be Regulated - 8.5 Recap - Learning Outcomes - Page 169: 3

Feedback inhibition takes place when the product of a reaction has an effect on the enzyme that helped produce it. This happens when the inhibitor binds to a second active site, changing the shape of the enzyme and preventing it from catalyzing the same reaction. The mechanism involved in feedback inhibition is common in metabolic pathways. For example, Figure 8.18 demonstrates an enzyme-catalyzed biosynthetic pathway that would fit into the commitment step, or the beginning of a metabolic pathway displayed in Figure 8.14.

Feedback inhibition takes place when the product of a reaction has an effect on the enzyme that helped produce it. This happens when the inhibitor binds to a second active site, changing the shape of the enzyme and preventing it from catalyzing the same reaction. The mechanism involved in feedback inhibition is common in metabolic pathways. For example, Figure 8.18 demonstrates an enzyme-catalyzed biosynthetic pathways that would fit into the commitment step, or the beginning of a metabolic pathway displayed in Figure 8.14.