Biology (11th Edition)

Published by McGraw-Hill Education
ISBN 10: 1-25918-813-2
ISBN 13: 978-1-25918-813-8

Chapter 16 - Control of Gene Expression - Review Questions - Synthesize: 1


Mutations in DNA binding sites for proteins would affect any other genes in the operon, and a plasmid with a wild type binding site would not affect these other genes since the wild type binding site would not be on a physically continuous piece of DNA with those other genes. This is an example of cis-dominance. In contrast, mutations in the binding proteins could be overcome by adding a plasmid with a wild type protein since it moves to the genes and does not have to be physically/covalently linked to them.

Work Step by Step

To understand this, the key is to see which case requires physical continuity: the mutations in the DNA binding site. A plasmid is useless for correcting this error since it will not be physically continuous with the affected genes. The protein in question, however, can move to the DNA, so a wild-type protein can correct the mutation in that case.
Update this answer!

You can help us out by revising, improving and updating this answer.

Update this answer

After you claim an answer you’ll have 24 hours to send in a draft. An editor will review the submission and either publish your submission or provide feedback.