Answer
12650
Work Step by Step
$253\times(45-7\times5)\times5$ $\longrightarrow$ resolve expression in parenthesis;multiply
$253\times(45-35)\times5$ $\longrightarrow$ resolve expression in parenthesis;subtract
$253\times10\times5$ $\longrightarrow$ multiply, working left to right
$2530\times5$
$12650$