Answer
$-120$
Work Step by Step
The determinant of a $2\times2$ matrix $A=\begin{bmatrix}a & b\\c&d
\end{bmatrix}$ is given by $ad-cb.$ Hence, the determinant of the given matrix, $
\begin{bmatrix}
-3&10\\6&20
\end{bmatrix}$ is
\begin{align*}\require{cancel}
&
-3(20)-6(10)
\\&=
-60-60
\\&=
-120
.\end{align*}