Le Grand Meaulnes was featured on the BBC Radio 4 programme Book at Bedtime, recorded in 1980 and repeated in 1999. A two-part serialisation by Jennifer Howarth was broadcast as the Classic Serial in August 2005.
The book was made into a film by Jean-Gabriel Albicocco in 1967. Another film adaptation, Le Grand Meaulnes, was released in November 2006, starring Jean-Baptiste Maunier, Clémence Poésy, and Nicolas Duvauchelle.
"Meaulnes the Great" is the title of a 2014 bas-relief (130 cm x 140 cm) carved in limewood by the French artist Jean-Louis Berthod from Albens, Savoy. The relief was inspired by Alain-Fournier's book and is a tribute to the missing people of World War I.
The book is the inspiration for the song 'My Yvonne', the ninth track from UK singer-songwriter Jack Peñate's debut album, Matinée, featuring backing vocals from a then-unknown Adele. Adele is not credited as a featured artist on the song; however, she is credited as a backing vocalist in the album's booklet.