- Susan Trinder - The protagonist of the novel
- Maud Lilly - The heiress whom Sue plans to defraud
- Richard 'Gentleman' Rivers - Partner in crime to both Sue and Maud
- Mrs Sucksby - Adoptive mother of Sue; Maud's real mother
- Mr Ibbs - The crooked pawn seller who runs the 'den of thieves' with Mrs Sucksby
- Christopher Lilly - Maud's 'uncle', in reality Sue's uncle; brother of Marianne Lilly
- Dainty - Sue's best friend in Lant Street; a petty thief and close friend of John Vroom
- John Vroom - An ill-tempered boy; also a petty thief
- Mrs Stiles - Maud's childhood carer; a bitter woman who never recovered from the loss of her own daughter
- Charles Way - A knife boy at Briar, who becomes enamoured with Gentleman
- Mr Way - A servant at Briar; father of Charles
- Agnes - Maud's long-suffering maid, who is seduced by Gentleman in order to make a post available for Sue
- Marianne Lilly - Susan's mother, whom Maud believed to be hers; her father and brother had her committed to an asylum after giving birth, where she died
- Mrs Cream - The owner of the cottage in which Gentleman and Maud stayed, on the night of their elopement, along with Sue; Charles' aunt.
- Dr Christie - Head doctor at the mental asylum where Sue is kept
- Nurse Spiller - One of the asylum's nurses who is particularly cruel to Sue
- Nurse Bacon - The ward nurse at the asylum who is more lazy than cruel
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