Lehninger Principles of Biochemistry 6th Edition

Published by W.H. Freeman
ISBN 10: 1-42923-414-8
ISBN 13: 978-1-42923-414-6

Chapter 27 - Protein Metabolism - Problems - Page 1151: 6

Answer

Polynucleotide phosphorylase does not require a primer. The composition of the mRNA created by this enzyme gives insight to the concentrations of nucleotide 5'-diphosphates that are present in solution. Because of this, a mixture of a high UDP:CDP ratio would yield the desired synthetic polymer.

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