how can such a statement change the world

So many people walk around with a meaningless life. They seem half-asleep, even when they're busy doing things they think are important. This is because they're chasing the wrong things. The way you get meaning in your life is to devote yourself to loving others, devote yourself to your community around you, and devote yourself to creating something that gives you purpose and meaning.

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This is a piece of advice Morrie gives to Mitch. He notices that people are just walking through life, not taking the time to notice the little things. They chase bigger things such as money or maybe fame. He says that in order to find meaning and joy in your life, you need to love others, be a positive part of your community, and be something bigger than yourself.