" anger keeps you lost" what does he mean?

Edwin is telling Cole that he will never win as long as he continues to be angry.

Cole has been "lost" throughout his life. His criminal behavior has gotten him "lost" on an island where he is sent for punishment. As long as he holds onto his anger, he will not be able to free himself from the past or from the crimes he has committed. He will be lost to all humanity and will shut himself off from everyone.