How are the descriptions of music and heroine similar? Do you think this story is a warning against drug use? What is the major fear the narrator has concerning his brother? Does he worry about people dying?

You have a lot of questions here. This is only a short answer space. I can comment on your first one. Despite the story's title, evidence in "Sonny's Blues" strongly suggests that it is jazz, more specifically bebop, that Sonny plays. For Baldwin, the blues are not a specific genre of music, but rather something more universal. The narrator explains that the blues are "the tale of how we suffer, and how we are delighted, and how we may triumph" (139). Given this definition, the story "Sonny's Blues" is itself a blues piece: it begins with the suffering of two brothers, follows their growing sense of communion, and ends with the triumph of brotherly love over alienation and pain. The narrator admits that this formula isn't innovative, but claims that "it's the only light we've got in all this darkness" (139). The story "Sonny's Blues" is an attempt, much like Sonny's actual music, to commune with its audience and, through that bridge of understanding and compassion, to relieve suffering. Baldwin is not playing, but writing the blues. The title "Sonny's Blues" refers not to the specific genre of music Sonny plays but to Sonny's story of suffering and triumph, of loss and redemption through music.