Oryx and Crake

How do we know that snowman is the survivor of an apocalypse and is the last genetically normal human?

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It opens with Snowman, who as far as he knows is the last fully human survivor of an apocalyptic event. Snowman is the sort of caretaker and lawgiver to a group of sentients he calls the Crakers. As the story unfolds , largely in flashback, we understand that all "natural" humans have perished from an apocalyptic virus save for Snowman (Jimmy) who was protected in a special place in the paradise complex.