Of Mice and Men

is it curley's wife because she is stuck in an unhappy marriage

who is the loneliest character in mice and men

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Last updated by Aslan
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I would have to go with Curley's wife being the loneliest. Her husband is abusive and the ranch, full of men, are afraid to talk to her. She is so isolated that Steinbeck does not even give her a name; she is simply known as Curley's property.